KMID : 0043320020250010049
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Archives of Pharmacal Research 2002 Volume.25 No. 1 p.49 ~ p.52
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Syntheses of (t)-Homoepibatidine Analogues
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Kim YH
Oh CY/Lee KY/Lee YS/Jung YH/Park HJ/Ham WH
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Abstract
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Syntheses of (¡¾)-homoepibatidine analogues (2), which contain the 8-azabicyclo [3.2. 1]octane ring system, were achieved by using palladium-catalyzed reductive-coupling reaction from 3 and the analgesic activity was tested by Mouse writhing antinociceptive assay.
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